Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642965 | 0.89 | SCD (0.41) | SCDSCD5HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL6645504 | 0.88 | TRPV4 (0.42) | SCDSCD5ALDH1A1MAPTRAB9A | |
| SCHEMBL7201167 | 0.83 | THRB (0.40) | ALDH1A1MAPTRAB9AKMT2ATDP1 | |
| SCHEMBL6648250 | 0.83 | L3MBTL1 (0.43) | HCRTR2HCRTR1ALDH1A1MAPTRAB9A | |
| SCHEMBL6644189 | 0.80 | AURKA (0.41) | SCDSCD5HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL6644600 | 0.80 | SCD (0.42) | SCDSCD5ALDH1A1MAPTRAB9A | |
| SCHEMBL6650001 | 0.78 | TRPV4 (0.45) | SCDSCD5 | |
| SCHEMBL6647477 | 0.75 | MEN1 (0.38) | ALDH1A1MAPTRAB9AKMT2ATDP1 | |
| SCHEMBL6649334 | 0.75 | SCD (0.42) | SCDSCD5HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL6647313 | 0.74 | SCD (0.40) | SCDSCD5HCRTR2HCRTR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |