Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358070 | 0.88 | PDGFRA (0.55) | CDK2PDGFRACCNE1ABL1BTK | |
| SCHEMBL7363250 | 0.86 | TK1 (0.53) | CDK2PDGFRACCNE1TK1CDK1 | |
| SCHEMBL7661515 | 0.83 | CCNE1 (0.54) | CDK2PDGFRACCNE1TK1CDK1 | |
| SCHEMBL7672863 | 0.81 | PDGFRA (0.52) | CDK2PDGFRACCNE1TK1TAAR1 | |
| SCHEMBL7674156 | 0.80 | HPGD (0.51) | CDK2PDGFRACCNE1CDK1 | |
| SCHEMBL24450806 | 0.78 | ADORA3 (0.56) | CDK2CCNE1CDK1CCNA2CCNA1 | |
| SCHEMBL5930393 | 0.78 | HSP90AA1 (0.49) | CDK2CCNE1TK1CDK1 | |
| SCHEMBL22133770 | 0.75 | CDK1 (0.56) | CDK2CCNE1CDK1CCNA2CCNA1 | |
| SCHEMBL7358271 | 0.75 | CCNE1 (0.51) | CDK2PDGFRACCNE1TK1CDK1 | |
| SCHEMBL7668634 | 0.74 | CCNE1 (0.54) | CDK2PDGFRACCNE1TK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579981-B1 | Treating herpes virus | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2003-06-17 | — | — | US | disclosed |