Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	ACP3	P15309	1/20	0.40

▸	ACHE	P22303	2/20	0.38

▸	GGPS1	O95749	1/20	0.38

▸	HPGD	P15428	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	TAS1R3	Q7RTX0	1/20	0.36

▸	TAS1R1	Q7RTX1	1/20	0.36

▸	TSHR	P16473	1/20	0.35

▸	PTPN5	P54829	1/20	0.34

▸	FDPS	P14324	1/20	0.33

▸	MMP1	P03956	1/20	0.33

▸	MMP2	P08253	1/20	0.33

▸	MMP3	P08254	1/20	0.33

▸	MMP7	P09237	1/20	0.33

▸	MMP9	P14780	1/20	0.33

▸	MMP8	P22894	1/20	0.33

▸	MMP13	P45452	1/20	0.33

▸	MMP14	P50281	1/20	0.33

▸	HDAC8	Q9BY41	1/20	0.33

▸	HDAC6	Q9UBN7	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Iodide SCHEMBL7193211	0.87	ACHE (0.46)	ACP3ACHEHPGDTDP1TAS1R3
Hydrochloric Acid SCHEMBL7192461	0.87	ACHE (0.46)	ACP3ACHEHPGDTDP1TAS1R3
Bromide SCHEMBL7195821	0.87	ACHE (0.46)	ACP3ACHEHPGDTDP1TAS1R3
Acetic Acid SCHEMBL8750089	0.84	HPGD (0.40)	ACP3ACHEHPGDTDP1TAS1R3
Acetic Acid SCHEMBL7195816	0.81	TDP1 (0.38)	ACP3ACHEHPGDTDP1TAS1R3
Succinic Acid SCHEMBL7195809	0.81	HPGD (0.38)	ACP3ACHEHPGDTDP1TAS1R3
Phosphoric Acid SCHEMBL7197899	0.80	ACP3 (0.43)	ACP3PTPN5LMNAMAPTHTT
Phosphoric Acid SCHEMBL7197978	0.80	RAB9A (0.40)	ACP3ACHEGGPS1PTPN5FDPS
Phosphoric Acid SCHEMBL7198172	0.80	ACP3 (0.40)	ACP3ACHEGGPS1HPGDTDP1
Phosphoric Acid SCHEMBL1067065	0.79	HIF1A (0.46)	HPGDTSHRLMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0624173-B2	PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS	DOW CHEMICAL CO (US)	2003-04-09	—	—	EP	disclosed
EP-0624173-B1	PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS	DOW CHEMICAL CO (US)	1997-04-02	—	—	EP	disclosed
EP-0624173-A1	PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS.	DOW CHEMICAL CO (US)	1994-11-17	—	—	EP	disclosed
US-5360886-A	Alklyphenylphosphine or phosphonium catalyst	THE DOW CHEMICAL COMPANY (US)	1994-11-01	—	—	US	disclosed
US-5310853-A	Epoxy resins	THE DOW CHEMICAL COMPANY (US)	1994-05-10	—	—	US	disclosed
WO-1993015126-A1	PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS	THE DOW CHEMICAL COMPANY (US)	1993-08-05	—	—	WO	disclosed
US-5202407-A	Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom	THE DOW CHEMICAL COMPANY (US)	1993-04-13	—	—	US	disclosed