Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632582 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL132773 | 0.85 | ALDH1A1 (0.78) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL7110777 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL100476 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1CYP3A4NPC1 | |
| SCHEMBL14205555 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL2518098 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9821352 | 0.80 | NPC1 (0.43) | ALDH1A1KMT2AMEN1MAPTMAOB | |
| SCHEMBL197163 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL126492 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1CYP3A4KDM4E | |
| SCHEMBL10604973 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372690-B | Intermediate for synthesizing imatinib and application of intermediate in imatinib synthesis | CHENGDU DIAO PHARMACEUTICAL GROUP CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-102372690-A | Intermediate for synthesizing imatinib and application of intermediate in imatinib synthesis | CHENGDU DIAO PHARMACEUTICAL GROUP CO LTD | 2012-03-14 | — | — | CN | disclosed |
| EP-2258804-A2 | Polymers for use in optical devices | Cambridge Display Technology Limited (GB) | 2010-12-08 | — | — | EP | disclosed |
| US-7795802-B2 | Polymers for use in optical devices | CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) | 2010-09-14 | — | — | US | disclosed |
| US-7795802-B2 | Polymers for use in optical devices | CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) | 2010-09-14 | — | — | US | disclosed |
| US-6600016-B1 | Solid support for use in the biosynthesis of combinatorial libraries | ADVANCED SYNTECH LLC | 2003-07-29 | — | — | US | disclosed |