SCHEMBL197163

SCHEMBL197163

CC(=O)OCc1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
NPSR1 Q6W5P4 2/20 0.55
MEN1 O00255 2/20 0.55
MAPT P10636 2/20 0.55
KMT2A Q03164 2/20 0.55
MAOA P21397 4/20 0.54
MAOB P27338 4/20 0.54
CYP3A4 P08684 2/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
MMP2 P08253 2/20 0.49
MMP1 P03956 1/20 0.49
MMP9 P14780 1/20 0.49
MMP12 P39900 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
GAA P10253 2/20 0.48
NR4A2 P43354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27589283 0.89 MAOB (0.71) ALDH1A1MAPTMAOAMAOBNR4A2
SCHEMBL132773 0.89 ALDH1A1 (0.78) ALDH1A1MEN1MAPTKMT2ACYP3A4
SCHEMBL20267648 0.83 IDO1 (0.52) ALDH1A1NPSR1MEN1MAPTKMT2A
SCHEMBL6646522 0.83 MEN1 (0.54) ALDH1A1NPSR1MEN1MAPTKMT2A
SCHEMBL28142 0.83 IDO1 (0.52) ALDH1A1NPSR1MEN1MAPTKMT2A
SCHEMBL126492 0.83 ALDH1A1 (0.69) ALDH1A1MEN1KMT2ACYP3A4IDO1
SCHEMBL4198688 0.83 ALDH1A1 (0.69) ALDH1A1MEN1MAPTKMT2ACYP3A4
SCHEMBL11315920 0.83 ALDH1A1 (0.69) ALDH1A1MEN1KMT2ACYP3A4L3MBTL1
SCHEMBL10604973 0.83 ALDH1A1 (0.69) ALDH1A1MEN1KMT2ACYP3A4L3MBTL1
SCHEMBL2997100 0.81 MAPT (0.54) ALDH1A1NPSR1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091704-A1 MANGANESE OXIDE LOADED COBALT-CHROMIUM CATALYST, PREPARATION THEREOF, AND USE THEREOF IN SYNTHESIS OF P-CHLOROBENZALDEHYDE 浙江大学 2025-05-08 WO disclosed
CN-117482956-A Manganese oxide loaded cobalt-chromium catalyst, preparation and application thereof in p-chlorobenzaldehyde synthesis 浙江大学 2024-02-02 CN disclosed
EP-3433250-B1 HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2021-09-08 EP disclosed
US-20210127673-A1 HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2021-05-06 US disclosed
EP-3341007-B1 MALT1 INHIBITORS AND USES THEREOF UNIV CORNELL (US) 2020-12-23 EP disclosed
US-10711036-B2 MALT1 inhibitors and uses thereof CORNELL UNIVERSITY (US) 2020-07-14 US disclosed
CN-111036298-A Preparation method and application of natural walnut shell powder sulfonic acid catalyst 华侨大学 2020-04-21 CN disclosed
US-20190327969-A1 HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
EP-2751076-B1 SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES MEDIMMUNE LTD (GB) 2018-04-25 EP disclosed
WO-2017162522-A1 HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2017-09-28 WO disclosed
US-20070149550-A1 1-aryl-4-cyclopropylpyrazoles with at least one fluorine attached to the cyclopropyl ring; parasiticides; fleas; extended duration of action for at least 28 days PFIZER INC. (US) 2007-06-28 US disclosed
WO-2007041775-A1 CYSTEINE PROTEASE INHIBITORS INCORPORATING AZIDE GROUPS THE UNIVERSITY OF QUEENSLAND (AU) 2007-04-19 WO disclosed
CN-1934105-A Aryl-substituted heterocycles, process for their preparation and their use as medicaments AVENTIS PHARMA GMBH (DE) 2007-03-21 CN disclosed
CN-1249066-C 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines PROCTER & GAMBLE (US) 2006-04-05 CN disclosed
CN-1556811-A 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines 2004-12-22 CN disclosed
CN-1549716-A 3-substituted 6, 7-dihydroxytetrahydroisoquinoline derivatives for use in antibacterial agents ��Ƥ�¹ɷ����޹�˾ 2004-11-24 CN disclosed
US-20040097557-A1 Cyanothiophene derivatives, compositions containing such compounds and methods of use DUFFY JOSEPH L (US) 2004-05-20 US disclosed
EP-0548774-B1 Process for producing a lactone or an ester SUMITOMO CHEMICAL CO (JP) 2000-03-15 EP disclosed
US-5405974-A Reacting a ketone, oxygen, an aromatic aldehyde using an aromatic solvent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-11 US disclosed
EP-0548774-A1 Process for producing a lactone or an ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149550-A1 1-aryl-4-cyclopropylpyrazoles with at least one fluorine attached to the cyclopropyl ring; parasiticides; fleas; extended duration of action for at least 28 days CYP3A43, CYP3A4, CYP2F1 ALDH1A1 559/4885NPSR1 849/4885MEN1 3272/4885
US-20190327969-A1 HERBICIDES DDT, HPD, PDXK ALDH1A1 345/4885NPSR1 3510/4885MEN1 4350/4885
US-10711036-B2 MALT1 inhibitors and uses thereof MALT1, BCL3, BCL6 ALDH1A1 2550/4885NPSR1 4604/4885MEN1 278/4885
US-20210127673-A1 HERBICIDES DDT, HPD, PDXK ALDH1A1 345/4885NPSR1 3510/4885MEN1 4350/4885
US-20040097557-A1 Cyanothiophene derivatives, compositions containing such compounds and methods of use GLP1R, GPR119, GCGR ALDH1A1 2652/4885NPSR1 292/4885MEN1 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.