SCHEMBL7201886

SCHEMBL7201886

CCOC(C)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
SLC37A4 O43826 1/20 0.40
POLB P06746 2/20 0.38
KDM4E B2RXH2 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 5/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TSHR P16473 1/20 0.36
NOTUM Q6P988 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011052 0.85 SLC37A4 (0.45) SLC37A4KDM4EMEN1KMT2ARECQL
SCHEMBL6469723 0.85 ALDH1A1 (0.44) LMNAPOLBKDM4EMEN1KMT2A
SCHEMBL29022997 0.82 CYP3A4 (0.40) LMNASLC37A4POLBKDM4EMEN1
SCHEMBL9011104 0.82 CA12 (0.43) SLC37A4KDM4EKMT2AALDH1A1CA12
SCHEMBL27719857 0.82 SLC37A4 (0.44) LMNASLC37A4POLBKDM4EMEN1
Ammonia Solution, Strong SCHEMBL27732589 0.81 CA12 (0.42) SLC37A4KDM4EKMT2AALDH1A1CA12
SCHEMBL8767672 0.81 LMNA (0.41) LMNASLC37A4POLBKDM4EMEN1
SCHEMBL17797855 0.80 ALDH1A1 (0.35) LMNAPOLBKDM4EMEN1KMT2A
SCHEMBL17797916 0.80 ALDH1A1 (0.35) LMNAPOLBKDM4EMEN1KMT2A
SCHEMBL1353325 0.79 TSHR (0.47) LMNASLC37A4POLBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365951-B2 Negative polarity on the nanofiber line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2016-06-14 US disclosed
US-20150211149-A1 Negative Polarity on the Nanofiber Line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-07-30 US disclosed
US-20150090658-A1 Fiber having a Nanohair Surface Topography KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-04-02 US disclosed
US-20030215506-A1 Methods and compositions for enhancement of creatine transport KUHRTS ERIC H (US) 2003-11-20 US disclosed
EP-0340618-B1 Organic composition containing a fluoroalkyl sulfonic acid salt DOW CHEMICAL CO (US) 1996-02-28 EP disclosed
EP-0586575-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-16 EP disclosed
WO-1992020738-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO disclosed
US-5068233-A For treatment of asthma, antiallergens or antihistamines ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0340618-A1 Organic composition containing a fluoroalkyl sulfonic acid salt THE DOW CHEMICAL COMPANY (US) 1989-11-08 EP disclosed
US-4806571-A ANTISTATIC AGENTS THE DOW CHEMICAL COMPANY (US) 1989-02-21 US disclosed
US-4618630-A ESPECIALLY FOR POLYURETHANE FOAM PRODUCTION THE DOW CHEMICAL CO. (US) 1986-10-21 US disclosed
WO-1986001521-A1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1986-03-13 WO disclosed