SCHEMBL8767672

SCHEMBL8767672

CCOC(c1ccccc1)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 3/20 0.38
MMP8 P22894 1/20 0.38
SLC37A4 O43826 1/20 0.38
KMT2A Q03164 4/20 0.38
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 3/20 0.38
RECQL P46063 1/20 0.38
CYP2D6 P10635 2/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7201886 0.81 LMNA (0.40) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL27719857 0.78 SLC37A4 (0.44) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8767637 0.77 SLC37A4 (0.42) LMNAKDM4EALDH1A1POLBSLC37A4
SCHEMBL6004163 0.75 POLB (0.47) LMNAKDM4EALDH1A1POLBSLC37A4
SCHEMBL7201769 0.75 ALDH1A1 (0.44) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL990486 0.75 POLB (0.46) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL421402 0.74 SLC37A4 (0.46) KDM4EALDH1A1POLBSLC37A4KMT2A
SCHEMBL28095505 0.74 ALDH1A1 (0.40) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1956043 0.73 TSHR (0.48) LMNAKDM4EALDH1A1HPGDPOLB
SCHEMBL3821055 0.73 POLB (0.45) LMNAKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed