Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202403 | 1.00 | ALDH1A1 (0.46) | ALDH1A1PKMSLC1A2KMT2ARAB9A | |
| SCHEMBL8904453 | 0.77 | SLC1A2 (0.40) | ALDH1A1PKMSLC1A2KMT2AMAPK1 | |
| SCHEMBL43958 | 0.74 | ALDH1A1 (0.38) | ALDH1A1PKMSLC1A2KMT2ACHRM2 | |
| SCHEMBL2283238 | 0.74 | ALDH1A1 (0.38) | ALDH1A1PKMSLC1A2KMT2ACHRM2 | |
| SCHEMBL20503163 | 0.70 | KMT2A (0.41) | ALDH1A1PKMKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10942606 | 0.69 | TSHR (0.44) | ALDH1A1KMT2ASMN1; SMN2MAPK1CA12 | |
| SCHEMBL9384480 | 0.68 | ALDH1A1 (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL18825262 | 0.68 | LMNA (0.65) | ALDH1A1PKMSLC1A2KMT2ALMNA | |
| SCHEMBL9632134 | 0.67 | LMNA (0.53) | ALDH1A1PKMSLC1A2KMT2AMAPK1 | |
| SCHEMBL6319092 | 0.67 | LMNA (0.52) | ALDH1A1PKMSLC1A2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1092723-A2 | Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |