Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 5/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202403 | 0.77 | ALDH1A1 (0.46) | SLC1A2ALDH1A1PKMMAPK1KMT2A | |
| SCHEMBL7202399 | 0.77 | ALDH1A1 (0.46) | SLC1A2ALDH1A1PKMMAPK1KMT2A | |
| SCHEMBL8132701 | 0.76 | MME (0.44) | ALDH1A1MMEACEHPGDMAPK1 | |
| SCHEMBL10939141 | 0.72 | MME (0.45) | ALDH1A1MMEACEHPGDMAPK1 | |
| SCHEMBL8887587 | 0.71 | KMT2A (0.40) | ALDH1A1PKMHPGDMAPTKMT2A | |
| SCHEMBL10505335 | 0.70 | MME (0.48) | ALDH1A1MMEACEHPGDMAPK1 | |
| Succinimide SCHEMBL8888235 | 0.70 | KMT2A (0.44) | ALDH1A1MMEMEN1MAPTKMT2A | |
| SCHEMBL1055212 | 0.69 | GPR139 (0.52) | ALDH1A1HPGDMAPK1MEN1MAPT | |
| SCHEMBL14417102 | 0.69 | GPR139 (0.52) | ALDH1A1HPGDMAPK1MEN1MAPT | |
| SCHEMBL8886846 | 0.69 | ABAT (0.39) | MMEHPGDMAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681927-A | COMPLEXES | NEORX CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| EP-0284071-B1 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORP (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5091514-A | Antitumor, anticarcinogenic agents | NEORX CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-4965392-A | DIAGNOSIS, RADIOTHERAPY OF TUMORS | NEORX CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0284071-A2 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORPORATION (US) | 1988-09-28 | — | — | EP | disclosed |