SCHEMBL7202715

SCHEMBL7202715

C=CCOC(=O)CC1=C(CCCCC)C(=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
RECQL P46063 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.35
HPGD P15428 1/20 0.33
THRB P10828 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
CDC25A P30304 6/20 0.31
CDC25B P30305 6/20 0.31
CDC25C P30307 5/20 0.31
THRA P10827 2/20 0.31
SCD O00767 1/20 0.31
NAAA Q02083 1/20 0.30
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175309 0.86 ALDH1A1 (0.38) TSHRTDP1ALDH1A1LMNAPOLB
SCHEMBL2142693 0.81 ALDH1A1 (0.38) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL4237197 0.76 ALDH1A1 (0.46) TSHRTDP1ALDH1A1LMNAPOLB
Acetic Acid SCHEMBL9004888 0.76 ALDH1A1 (0.42) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL8429054 0.76 ALOX5 (0.44) TSHRTDP1ALDH1A1LMNAHSD17B10
Lithium Ion SCHEMBL8677043 0.74 GPR84 (0.46) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL7187409 0.72 SCD (0.40) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL4297676 0.71 ALDH1A1 (0.40) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL4441878 0.70 ALDH1A1 (0.39) TDP1ALDH1A1LMNAPOLBRECQL
SCHEMBL11765129 0.69 SCD (0.45) TDP1ALDH1A1LMNAPOLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586620-B1 Isomerisation of methyl 3-acetoxy-2,3-epoxy-2-pentyl-1-cyclopentaneacetate to give jasmonic acid, methyl ester used in perfumes FIRMENICH SA (CH) 2003-07-01 US disclosed
US-6586620-B1 Isomerisation of methyl 3-acetoxy-2,3-epoxy-2-pentyl-1-cyclopentaneacetate to give jasmonic acid, methyl ester used in perfumes FIRMENICH SA (CH) 2003-07-01 US disclosed
EP-0583564-B1 Process for the preparation of 3-oxo-2-pentyl-1-cyclopentene alkyl acetates FIRMENICH & CIE (CH) 1996-10-09 EP disclosed
EP-0583564-A1 Process for the preparation of 3-oxo-2-pentyl-1-cyclopentene alkyl acetates FIRMENICH SA (CH) 1994-02-23 EP disclosed