Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | C5 | P01031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202476 | 0.95 | CNR1 (0.40) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6171169 | 0.76 | AKR1C3 (0.46) | PTGS1ALDH1A1 | |
| SCHEMBL7202731 | 0.73 | LMNA (0.39) | PTGS2MAPTKMT2APSEN1PSEN2 | |
| SCHEMBL6172688 | 0.72 | AKR1C3 (0.49) | MAPTPTGS1ALDH1A1 | |
| SCHEMBL6169150 | 0.72 | AKR1C3 (0.44) | PTGS1ALDH1A1 | |
| SCHEMBL7241953 | 0.70 | KMT2A (0.48) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL2000060 | 0.69 | BAZ2B (0.38) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL6169838 | 0.68 | AKR1C3 (0.47) | MAPTPTGS1ALDH1A1 | |
| SCHEMBL25139928 | 0.68 | PSEN1 (0.45) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL30708155 | 0.68 | PSEN1 (0.45) | MEN1KMT2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | claimed |
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |