Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202738 | 0.95 | PTGS2 (0.40) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6169150 | 0.77 | AKR1C3 (0.44) | IDEPTGS1 | |
| SCHEMBL6169838 | 0.74 | AKR1C3 (0.47) | IDEHPGDMAPTPTGS1 | |
| SCHEMBL6171169 | 0.72 | AKR1C3 (0.46) | PTGS1 | |
| SCHEMBL7202731 | 0.71 | LMNA (0.39) | PTGS2MAPTKMT2A | |
| SCHEMBL7241953 | 0.69 | KMT2A (0.48) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6172688 | 0.68 | AKR1C3 (0.49) | HPGDMAPTPTGS1 | |
| SCHEMBL2000060 | 0.68 | BAZ2B (0.38) | PTGS2HPGDSMN1; SMN2MEN1MAPT | |
| SCHEMBL25139928 | 0.67 | PSEN1 (0.45) | IDEHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30708155 | 0.67 | PSEN1 (0.45) | IDEHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | claimed |
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |