Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205218 | 1.00 | ADRB2 (0.38) | ADRB2ADRB1ADRB3LSSHTR2A | |
| SCHEMBL7208512 | 0.87 | L3MBTL1 (0.37) | LSSHTR2AHTR2CHPGDSIGMAR1 | |
| SCHEMBL7206925 | 0.87 | L3MBTL1 (0.37) | LSSHTR2AHTR2CHPGDSIGMAR1 | |
| SCHEMBL7204206 | 0.87 | L3MBTL1 (0.37) | LSSHTR2AHTR2CHPGDSIGMAR1 | |
| SCHEMBL4797053 | 0.87 | LSS (0.48) | LSS | |
| SCHEMBL4798383 | 0.87 | LSS (0.48) | LSS | |
| SCHEMBL4802247 | 0.87 | LSS (0.48) | LSS | |
| SCHEMBL4797704 | 0.86 | LSS (0.46) | LSS | |
| SCHEMBL7205761 | 0.85 | SIGMAR1 (0.40) | HPGDSIGMAR1 | |
| SCHEMBL7209032 | 0.85 | HTR2A (0.48) | LSSHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |