Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204206 | 1.00 | L3MBTL1 (0.37) | L3MBTL1SIGMAR1HPGDALDH1A1LTA4H | |
| SCHEMBL7208512 | 1.00 | L3MBTL1 (0.37) | L3MBTL1SIGMAR1HPGDALDH1A1LTA4H | |
| SCHEMBL7205761 | 0.90 | SIGMAR1 (0.40) | SIGMAR1HPGDALDH1A1 | |
| SCHEMBL4798905 | 0.88 | LSS (0.46) | LSS | |
| SCHEMBL4804021 | 0.88 | LSS (0.46) | LSS | |
| SCHEMBL4808855 | 0.88 | LSS (0.46) | LSS | |
| SCHEMBL7203078 | 0.87 | ADRB2 (0.38) | SIGMAR1HPGDLSSHTR2AHTR2C | |
| SCHEMBL7205218 | 0.87 | ADRB2 (0.38) | SIGMAR1HPGDLSSHTR2AHTR2C | |
| SCHEMBL4803138 | 0.87 | LSS (0.44) | HPGDUSP2HSD17B10LSS | |
| SCHEMBL7209017 | 0.85 | TSHR (0.37) | L3MBTL1HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |