SCHEMBL7203232

SCHEMBL7203232

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Zr](Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
TSHR P16473 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556848 0.88 KIF11 (0.33) RAB9ASMN1; SMN2
SCHEMBL16394005 0.88 RXRB (0.31)
SCHEMBL6889133 0.86 EDNRB (0.32)
Hydrochloric Acid SCHEMBL8167628 0.85 BRD4 (0.32) BRD4CREBBP
SCHEMBL27463750 0.85 PTGS2 (0.33) TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL3163967 0.84 BRD4 (0.33) BRD4
SCHEMBL2234772 0.84 BRD4 (0.32) BRD4CREBBPNPC1LMNATP53
SCHEMBL7199373 0.83 HTR2C (0.34)
SCHEMBL7934286 0.83 MAOA (0.30) TSHRNPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL2232423 0.83 BRD4 (0.31) BRD4CREBBPNPC1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234671-A Method for producing skin/foam/skin structures with high surface finish 道达尔能源一技术比利时公司 2023-06-06 CN disclosed
EP-3673013-B1 POLYPROPYLENE COMPOSITION WITH IMPROVED OPTICAL AND IMPACT BEHAVIOUR BOREALIS AG (AT) 2023-05-03 EP disclosed
CN-110167973-B High purity polypropylene for molding and polypropylene composition 道达尔研究技术弗吕公司 2022-06-17 CN disclosed
EP-3673013-A1 POLYPROPYLENE COMPOSITION WITH IMPROVED OPTICAL AND IMPACT BEHAVIOUR Borealis AG (AT) 2020-07-01 EP disclosed
WO-2019038134-A1 POLYPROPYLENE COMPOSITION WITH IMPROVED OPTICAL AND IMPACT BEHAVIOUR BOREALIS AG (AT) 2019-02-28 WO disclosed
EP-1828266-B1 SUPPORTED METALLOCENE CATALYST COMPOSITIONS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2015-07-22 EP disclosed
CN-102257014-B Catalyst system for olefin polymerization, its production and use BASELL POLYOLEFINE GMBH 2014-06-04 CN disclosed
CN-101384624-B Catalyst composition for olefin polymerization NOVOLEN TECH HOLDINGS CV 2012-07-04 CN disclosed
CN-100575324-C Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH 2009-12-30 CN disclosed
CN-101384624-A Catalyst composition for olefin polymerization NOVOLEN TECH HOLDINGS CV (NL) 2009-03-11 CN disclosed
CN-1249096-C Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2006-04-05 CN disclosed
CN-1590355-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
CN-1590422-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
US-20030236378-A1 For producing propylene polymers that are suited for fiber spinning BASELL POLYOLEFINE GMBH (DE) 2003-12-25 US disclosed
CN-1433435-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-07-30 CN disclosed
US-20010007009-A1 Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium BASF AKTIENGESELLSCHAFT (DE) 2001-07-05 US disclosed