Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205976 | 1.00 | CTSL (0.50) | CTSLCTSBCTSSCTSKKDM1A | |
| SCHEMBL7205858 | 0.87 | CTSS (0.47) | CTSLCTSBCTSSCTSKMMP9 | |
| SCHEMBL7205866 | 0.87 | CTSS (0.47) | CTSLCTSBCTSSCTSKMMP9 | |
| SCHEMBL7203966 | 0.85 | MMP9 (0.53) | MMP9MMP8MMP14OPRK1CYP3A4 | |
| SCHEMBL7203960 | 0.85 | MMP9 (0.53) | MMP9MMP8MMP14OPRK1CYP3A4 | |
| SCHEMBL14513403 | 0.85 | MMP9 (0.63) | MMP9MMP8MMP14LMNACAPN1 | |
| SCHEMBL5587642 | 0.85 | MMP9 (0.63) | MMP9MMP8MMP14LMNACAPN1 | |
| Hydrochloric Acid SCHEMBL7205259 | 0.83 | MMP9 (0.51) | KDM1AMAOAMMP9MMP8MMP14 | |
| Hydrochloric Acid SCHEMBL8199774 | 0.83 | MMP9 (0.51) | KDM1AMAOAMMP9MMP8MMP14 | |
| SCHEMBL7203001 | 0.83 | MMP9 (0.55) | MMP9MMP8MMP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |