Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205858 | 1.00 | CTSS (0.47) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL8200710 | 0.90 | ACE (0.53) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL8200707 | 0.90 | ACE (0.53) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL7204510 | 0.88 | CTSS (0.41) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL7204513 | 0.88 | CTSS (0.41) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL8205976 | 0.87 | CTSL (0.50) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL7203421 | 0.87 | CTSL (0.50) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL7204598 | 0.86 | MAPT (0.51) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL7202882 | 0.85 | CTSL (0.44) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL7209769 | 0.85 | CCKBR (0.45) | CTSSCTSKCTSLCTSBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |