Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19323971 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL7265062 | 0.71 | LMNA (0.54) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL16935394 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL19323689 | 0.69 | KDM4E (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL9453164 | 0.68 | ALOX15 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL16740898 | 0.67 | KDM4E (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL7271706 | 0.67 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C19 | |
| SCHEMBL8740908 | 0.67 | PTK2 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL7265243 | 0.66 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL16935203 | 0.66 | ALDH1A1 (0.96) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |