Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013645 | 0.84 | HIF1A (0.49) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL9715643 | 0.81 | CA2 (0.64) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL19612211 | 0.79 | KDM4E (0.61) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL7166937 | 0.76 | NQO1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7009749 | 0.76 | KDM4E (0.45) | HIF1AKDM4EMAPTLMNATSHR | |
| SCHEMBL7013648 | 0.74 | HIF1A (0.49) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL1787478 | 0.73 | KDM4E (0.50) | HIF1ACA12CA1CA7CA9 | |
| SCHEMBL28891596 | 0.73 | KDM4E (0.50) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL7203444 | 0.73 | HIF1A (0.54) | HIF1ACA12CA1CA2CA7 | |
| SCHEMBL13634446 | 0.73 | APLNR (0.50) | HIF1AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |