Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8086568 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2354752 | 0.94 | — | — | |
| Bicarbonate SCHEMBL120119 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6577639 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL81419 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2304976 | 0.89 | — | — | |
| Bicarbonate SCHEMBL570556 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2050659 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17868581 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3732974 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150037231-A1 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | CALERA CORPORATION | 2015-02-05 | — | — | US | disclosed |
| US-8883104-B2 | Gas stream multi-pollutants control systems and methods | CALERA CORPORATION (US) | 2014-11-11 | — | — | US | disclosed |
| US-8491858-B2 | Gas stream multi-pollutants control systems and methods | CALERA CORPORATION (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120049114-A1 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | ARELAC, INC. | 2012-03-01 | — | — | US | disclosed |
| US-20110226989-A9 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | ARELAC, INC. | 2011-09-22 | — | — | US | disclosed |
| EP-2250127-A1 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | Calera Corporation (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2010101953-A1 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | CALERA CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |
| US-20100219373-A1 | GAS STREAM MULTI-POLLUTANTS CONTROL SYSTEMS AND METHODS | CALERA CORPORATION | 2010-09-02 | — | — | US | disclosed |