Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2354752 | 1.00 | — | — | |
| Bicarbonate SCHEMBL2304976 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6577639 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6579968 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL81419 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17868581 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL720363 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL570556 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2050659 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3732974 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083648-A1 | DEODORANT COMPOSITIONS AND METHODS OF MAKING SAME | DR. SQUATCH, LLC (US) | 2026-03-26 | — | — | US | claimed |
| EP-4714422-A1 | COMPOSITION FOR ABSORBING SKIN PERSPIRATION AND/OR BODY MOISTURE | Società Italo Britannica L. Manetti - H. Roberts & C.p.A. (IT) | 2026-03-25 | — | — | EP | claimed |
| US-20250375362-A1 | DEODORANT COMPOSITIONS | PROCTER & GAMBLE (US) | 2025-12-11 | — | — | US | claimed |
| US-20250352457-A1 | DEODORANT COMPOSITIONS AND METHODS OF MAKING SAME | DR. SQUATCH, LLC (US) | 2025-11-20 | — | — | US | claimed |
| EP-4628066-A2 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS | The Procter & Gamble Company (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250303676-A1 | LAMINATE, USE THEREOF, AND METHOD OF MAKING THE SAME | HEXION INC. | 2025-10-02 | — | — | US | claimed |
| US-12420534-B2 | Aerogel polysiloxane layer laminate structure | DOW SILICONES CORPORATION (US) | 2025-09-23 | — | — | US | claimed |
| EP-3768389-B1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS | PROCTER & GAMBLE (US) | 2025-09-03 | — | — | EP | claimed |
| EP-3695832-B1 | COMPOSITION FOR TREATING HAIR LOSS | DUI CLINIQUE AS (NO) | 2025-06-18 | — | — | EP | claimed |
| US-20250170524-A1 | SYSTEM, APPARATUS, AND METHOD FOR ALKALINE EARTH METAL HYDROXIDE LOOPING FOR CARBON DIOXIDE REMOVAL FROM AIR | PARALLEL CARBON INC (US) | 2025-05-29 | — | — | US | claimed |
| US-4629628-A | HIGH STRENGTH | FERRERO OHG MBH (DE) | 1986-12-16 | — | — | US | claimed |
| EP-0111747-B1 | STORAGE-STABLE AGENT CONTAINING PYRAZOPHOS AND CAPTAFOL AS ACTIVE INGREDIENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-30 | — | — | EP | claimed |
| EP-0160015-A1 | PREPARATION FOR REHYDRATING MONOGASTRIC ANIMALS, INCLUDING HUMAN BEINGS, SUFFERING FROM DIARRHOEA AND USE THEREOF. | GJERLOV MOGENS | 1985-11-06 | — | — | EP | claimed |
| EP-0150792-A2 | Drugs and the use of poorly soluble compounds of calcium and/or magnesium for the production of drugs | Algina Aktiengesellschaft (CH) | 1985-08-07 | — | — | EP | claimed |
| WO-1985001441-A1 | PREPARATION FOR REHYDRATING MONOGASTRIC ANIMALS, INCLUDING HUMAN BEINGS, SUFFERING FROM DIARRHOEA AND USE THEREOF | GJERLOEV MOGENS | 1985-04-11 | — | — | WO | claimed |
| EP-0111747-A1 | Storage-stable agent containing pyrazophos and captafol as active ingredients | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-27 | — | — | EP | claimed |
| EP-0022901-B1 | WAFFLE AND PROCESS FOR ITS PRODUCTION | Ferrero oHG (DE) | 1984-06-20 | — | — | EP | claimed |
| EP-0011748-B1 | PROCESS FOR PRODUCING POLYOLEFIN FOAMS | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-12-01 | — | — | EP | claimed |
| US-4266041-A | USING PEROXIDE CROSSLINKING AND FOAMING AGENTS UNDER NORMAL PRESSURE WITH MAGNESIUM OXIDE, HYDROXIDE OR BASIC CARBONATE PRESENT | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | claimed |
| EP-0022901-A2 | Waffle and process for its production | Ferrero oHG (DE) | 1981-01-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083648-A1 | DEODORANT COMPOSITIONS AND METHODS OF MAKING SAME | CUTA, DAGLA, LIPA | CA4 1409/4885CA1 2680/4885FAHD1 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.