SCHEMBL7203878

SCHEMBL7203878

C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)c(O)c3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 1.00
PTPN1 P18031 3/20 0.88
GSK3B P49841 2/20 0.88
CYP19A1 P11511 1/20 0.88
UBE2N P61088 1/20 0.88
SLCO2B1 O94956 2/20 0.79
SYNJ2 O15056 1/20 0.79
DPP4 P27487 1/20 0.75
KDM1A O60341 2/20 0.69
POLB P06746 1/20 0.65
CALM1 P0DP23 1/20 0.65
CACNA1B Q00975 1/20 0.65
APBA1 Q02410 1/20 0.65
CTDSP1 Q9GZU7 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
XDH P47989 2/20 0.64
TRPA1 O75762 1/20 0.51
P4HB P07237 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20437861 1.00 PKM (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
SCHEMBL29366330 1.00 PKM (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL20386954 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL1201445 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL13237107 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL23431 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL16592383 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL2614060 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL20383126 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N
Naringin SCHEMBL14114613 0.94 PTPN1 (1.00) PKMPTPN1GSK3BCYP19A1UBE2N

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) 2025-11-06 US disclosed
WO-2021144447-A1 PLANT EXTRACT COMPOSITION FOR THE TREATMENT OF CARDIOVASCULAR AND METABOLIC DISEASES MEDA Pharma S.p.A. (IT) 2021-07-22 WO disclosed
WO-2021144446-A1 PLANT EXTRACT COMPOSITION FOR THE TREATMENT OF LIVER STEATOSIS MEDA Pharma S.p.A. (IT) 2021-07-22 WO disclosed
CN-107929301-A Application of the neoeriocitrin in protein expression conditioning agent is prepared 黑龙江葆纳生物科技有限责任公司 2018-04-20 CN disclosed
EP-1286706-A2 GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS The American National Red Cross (US) 2003-03-05 EP disclosed
WO-2001087357-A2 GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS THE AMERICAN NATIONAL RED CROSS (US) 2001-11-22 WO disclosed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM S100A8, TP53, AQP1 PKM 3085/4885PTPN1 2775/4885GSK3B 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.