Hexane

Hexane

SCHEMBL720450

CC(C)O.CCCCCC.O=CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.46
DDAH1 O94760 1/20 0.46
GAPDH P04406 1/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 2/20 0.43
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ADH4 P08319 2/20 0.43
ADH7 P40394 2/20 0.43
GPR84 Q9NQS5 3/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR1 O14842 1/20 0.41
CA1 P00915 1/20 0.41
EPHX1 P07099 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL5203374 0.97 TSHR (0.48) TRPA1DDAH1GAPDHMAPTTSHR
Hexane SCHEMBL30665128 0.87 TSHR (0.53) TSHRADH1BADH1CADH1AADH4
Hexane SCHEMBL2439199 0.87
Butyl Alcohol SCHEMBL17673151 0.87 ALDH1A1 (0.55) TRPA1DDAH1GAPDHMAPTTSHR
Hexane SCHEMBL28985132 0.86 ADH1B (0.39) TRPA1DDAH1GAPDHMAPTTSHR
Heptane SCHEMBL7200232 0.86 SPHK1 (0.42) TRPA1DDAH1GAPDHMAPTTSHR
2-Heptanol SCHEMBL28641247 0.85 TRPA1 (0.50) TRPA1DDAH1GAPDHMAPTADH1B
Octane SCHEMBL2485910 0.84 TSHR (0.58) TSHRADH1BADH1CADH1AADH4
Hexane SCHEMBL2521059 0.84 TSHR (0.50) TRPA1TSHRADH1BADH1CADH1A
Decane SCHEMBL30414302 0.84 TSHR (0.58) TSHRADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111229188-B Glycopeptide antibiotic functionalized magnetic composite material and preparation method and application thereof 天津大学 2022-03-29 CN disclosed
EP-3116854-B1 NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) 2022-01-26 EP disclosed
CN-111229188-A Glycopeptide antibiotic functionalized magnetic composite material and preparation method and application thereof 天津大学 2020-06-05 CN disclosed
US-20170037002-A1 NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) 2017-02-09 US disclosed
EP-2535053-A1 MITOCHONDRIAL FUNCTION IMPROVER Kao Corporation (JP) 2012-12-19 EP disclosed
US-20120302513-A1 Mitochondrial Function Improver KAO CORPORATION (JP) 2012-11-29 US disclosed
US-8268360-B2 Motor function improver KAO CORPORATION (JP) 2012-09-18 US disclosed
US-20120052129-A1 Motor Function Improver KAO CORPORATION (JP) 2012-03-01 US disclosed
US-20070269503-A1 Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof IMASIGHT INC. (CA) 2007-11-22 US disclosed
EP-0828704-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1998-03-18 EP disclosed
US-5629447-A Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid WARNER-LAMBERT COMPANY (US) 1997-05-13 US disclosed
WO-1996038405-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1996-12-05 WO disclosed
WO-1989009263-A1 MOLECULAR CLONING AND EXPRESSION OF GENES ENCODING LIPOLYTIC ENZYMES GIST-BROCADES N.V. (NL) 1989-10-05 WO disclosed
EP-0334462-A1 Molecular cloning and expression of genes encoding lipolytic enzymes GENENCOR INTERNATIONAL, INC. (US) 1989-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037002-A1 NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS PTGES3, PTGER3, PTGES TRPA1 3781/4885DDAH1 3140/4885GAPDH 1516/4885
US-20070269503-A1 Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof LDLR, HMGCR, CETP TRPA1 4872/4885DDAH1 2485/4885GAPDH 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.