Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.30 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561871 | 0.81 | CRBN (0.50) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL8988103 | 0.78 | CRBN (0.47) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL10694738 | 0.78 | CRBN (0.47) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL7715133 | 0.78 | CRBN (0.47) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL3414870 | 0.78 | CRBN (0.47) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL7715134 | 0.78 | CRBN (0.47) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL7204552 | 0.75 | CRBN (0.48) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL28242393 | 0.75 | CRBN (0.54) | CRBNDDB1PKML3MBTL1ALDH1A1 | |
| SCHEMBL19348252 | 0.73 | CRBN (0.43) | CRBNDDB1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9486303 | 0.73 | CRBN (0.47) | CRBNDDB1PKMDUTSLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |