SCHEMBL7715134

SCHEMBL7715134

O=c1ccn(C=CI)c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.47
DDB1 Q16531 1/20 0.42
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA9 Q16790 1/20 0.33
DUT P33316 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715133 1.00 CRBN (0.47) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL10694738 0.83 CRBN (0.47) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL10694735 0.83 CRBN (0.47) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL3414870 0.79 CRBN (0.47) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL8988103 0.79 CRBN (0.47) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL19348252 0.79 CRBN (0.43) CRBNDDB1ALDH1A1LMNACA1
SCHEMBL2561871 0.78 CRBN (0.50) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL7984568 0.78 CRBN (0.45) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL10657246 0.77 CRBN (0.48) CRBNDDB1ALDH1A1LMNAPKM
SCHEMBL7204552 0.77 CRBN (0.48) CRBNDDB1ALDH1A1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746319-A4 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER KARL Y (US) 1997-11-05 EP claimed
EP-0746319-A1 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER, Karl Y. (US) 1996-12-11 EP claimed
WO-1994026273-A1 ACYCLOVIR DERIVATIVES FOR TOPICAL USE HOSTETLER KARL Y (US) 1994-11-24 WO claimed
EP-1194174-A2 EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD The University Of Alberta, Simon Fraser Uni., The Uni. of Victoria, And The Uni. Of British Columbia doing business as TRIUMF (CA) 2002-04-10 EP disclosed
WO-2000078364-A2 EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD THE UNIVERSITY OF ALBERTA; SIMON FRASER UNIVERSITY; THE UNIVERSITY OF VICTORIA; THE UNIVERSITY OF BRITISH COLUMBIA DOING BUSINESS AS TRIUMF (CA) 2000-12-28 WO disclosed