Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211184 | 0.95 | PAOX (0.56) | CASP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12829898 | 0.95 | CASP2 (0.46) | CASP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5493471 | 0.92 | SLC6A5 (0.47) | CASP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13788598 | 0.89 | PRMT1 (0.57) | MEN1KMT2AALDH1A1SLC6A5TSHR | |
| SCHEMBL7700850 | 0.89 | CASP2 (0.70) | CASP2MEN1KMT2ASLC6A5NAAA | |
| SCHEMBL9497865 | 0.88 | NAAA (0.48) | CASP2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24412649 | 0.87 | CASP2 (0.74) | CASP2SLC6A5NAAAHPGD | |
| SCHEMBL17817620 | 0.87 | CASP2 (0.74) | CASP2SLC6A5NAAAHPGD | |
| SCHEMBL20663420 | 0.87 | PRMT1 (0.61) | MEN1KMT2AALDH1A1SLC6A5TSHR | |
| SCHEMBL11739321 | 0.87 | CASP2 (0.74) | CASP2SLC6A5NAAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |