SCHEMBL720471

SCHEMBL720471

Cc1ccn(-c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 3/20 0.48
HPGD P15428 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CYP1A2 P05177 2/20 0.45
KDM4E B2RXH2 1/20 0.45
BLM P54132 1/20 0.45
HSD17B10 Q99714 1/20 0.45
DRD4 P21917 5/20 0.41
CYP3A4 P08684 1/20 0.40
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
ACHE P22303 1/20 0.39
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18850042 0.83 MGLL (0.43) COMTHPGDALDH1A1CYP1A2KDM4E
SCHEMBL19454426 0.77 ACHE (0.44) HPGDALDH1A1KDM4ELMNAACHE
SCHEMBL3228458 0.77 NOTUM (0.44) ALDH1A1KDM4ECYP3A4LMNAALOX12
SCHEMBL10207531 0.76 MAPT (0.60) ALDH1A1KDM4ECYP3A4TSHRACHE
SCHEMBL1670288 0.74 CYP1A2 (0.52) HPGDALDH1A1CYP1A2KDM4EBLM
SCHEMBL14827196 0.74 COMT (0.61) COMTHPGDALDH1A1CYP1A2KDM4E
SCHEMBL720718 0.72 NPC1 (0.41) COMTHPGDALDH1A1CYP1A2KDM4E
SCHEMBL24257858 0.71 COMT (0.48) COMTHPGDALDH1A1CYP1A2DRD4
SCHEMBL2847343 0.71 COMT (0.48) COMTHPGDCYP1A2DRD4CYP3A4
SCHEMBL17267004 0.71 COMT (0.48) COMTHPGDALDH1A1DRD4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041970-A A kind of high efficiency methanol gasoline and preparation method thereof 中润油新能源股份有限公司 2019-07-23 CN claimed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
CN-110294748-A A kind of synthetic method for Ge Lieting key intermediate 浙江沙星科技有限公司 2019-10-01 CN disclosed
CN-105986253-B The plating application and its manufacturing method of excellent adhesion 阿基里斯株式会社 2019-09-27 CN disclosed
CN-106866534-B The preparation method of C-4 thio pyrazole compounds 曲阜师范大学 2019-07-09 CN disclosed
CN-109942571-A The preparation method for treating the drug Te Lilieting of diabetes 深圳市第二人民医院 2019-06-28 CN disclosed
WO-2019028062-A1 PIRFENIDONE DERIVATIVES FOR MODULATION OF B LYMPHOCYTE ACTIVITY AND ORGAN PROTECTION WASHINGTON UNIVERSITY (US) 2019-02-07 WO disclosed
US-10167303-B2 Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex UDC IRELAND LIMITED (IE) 2019-01-01 US disclosed
CN-109053694-A The method that one kettle way prepares indoline system methine dyes 宁波龙欣精细化工有限公司 2018-12-21 CN disclosed
EP-1779392-A1 PROCESS FOR COATING FINE PARTICLES WITH CONDUCTIVE POLYMERS Chemetall GmbH (DE) 2007-05-02 EP disclosed
EP-1778413-A1 PROCESS FOR COATING METALLIC SURFACES WITH AN ANTI-CORROSIVE COATING Chemetall GmbH (DE) 2007-05-02 EP disclosed
EP-1776196-A2 METHOD FOR PROTECTING A METAL SURFACE BY MEANS OF A CORROSION-INHIBITING COATING Chemetall GmbH (DE) 2007-04-25 EP disclosed
US-7166617-B2 Cyclic amide derivatives MITSUBISHI PHARMA CORPORATION (JP) 2007-01-23 US disclosed
WO-2006015754-A2 METHOD FOR PROTECTING A METAL SURFACE BY MEANS OF A CORROSION-INHIBITING COATING CHEMETALL GMBH (DE) 2006-02-16 WO disclosed
WO-2006015756-A1 PROCESS FOR COATING METALLIC SURFACES WITH AN ANTI-CORROSIVE COATING CHEMETALL GMBH (DE) 2006-02-16 WO disclosed
WO-2006015757-A1 PROCESS FOR COATING FINE PARTICLES WITH CONDUCTIVE POLYMERS CHEMETALL GMBH (DE) 2006-02-16 WO disclosed
EP-0261837-B1 Process for the preparation of electrically conductive material SANYO ELECTRIC CO (JP) 2001-07-11 EP disclosed
US-4795687-A POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION MITSUBISHI KASEI CORP. (JP) 1989-01-03 US disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167303-B2 Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex NDUFS5, DDT, NDUFV2 COMT 333/4885HPGD 454/4885ALDH1A1 367/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 COMT 3365/4885HPGD 2577/4885ALDH1A1 3072/4885
US-11771738-B2 Endoparasitic depsipeptides VIP, PREP, VIPR1 COMT 4034/4885HPGD 1639/4885ALDH1A1 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.