Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887320 | 0.78 | TDP1 (0.50) | CYP1A2CYP2C9ACHETUBB4ATUBB | |
| SCHEMBL28198750 | 0.76 | TUBB4A (0.54) | CYP1A2CYP2C9ACHETUBB4ATUBB | |
| SCHEMBL19454426 | 0.75 | ACHE (0.44) | ACHETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28140519 | 0.75 | ACHE (0.44) | ACHETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30149589 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2C9TUBB4ATUBBTUBA3C | |
| SCHEMBL5116483 | 0.74 | ALDH1A1 (0.55) | CYP1A2CYP2C9ACHETUBB4ATUBB | |
| SCHEMBL2092151 | 0.74 | MAPT (0.60) | CYP1A2CYP2C9ACHEMGLLCA12 | |
| SCHEMBL720471 | 0.74 | COMT (0.48) | CYP1A2CYP2C9ACHETUBB4ATUBB | |
| SCHEMBL28455373 | 0.73 | MGLL (0.57) | CYP1A2CYP2C9ACHETUBB4ATUBB | |
| SCHEMBL3264192 | 0.73 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |