Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102101 | 0.78 | SMPD1 (0.40) | SMPD1PDE4DKMT2ACYP3A4 | |
| SCHEMBL9101386 | 0.75 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL4738884 | 0.71 | ALOX5 (0.40) | ALOX5GAAKDM4EPKMMGAM | |
| SCHEMBL9967702 | 0.68 | ALOX5 (0.60) | ALOX5NFKB1NFKB2RELAGAA | |
| SCHEMBL5749454 | 0.68 | ALOX5 (0.42) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL2211615 | 0.67 | ALOX5 (0.41) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL16116143 | 0.67 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL6427404 | 0.66 | ALOX5 (0.41) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL9101999 | 0.65 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL2214744 | 0.65 | ALOX5 (0.39) | ALOX5NFKB1NFKB2RELASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |
| US-6602515-B2 | Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives | EM INDUSTRIES | 2003-08-05 | — | — | US | disclosed |