Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204880 | 0.78 | ALOX5 (0.39) | SMPD1PDE4DCYP3A4KMT2A | |
| SCHEMBL9103459 | 0.73 | ALOX5 (0.51) | — | |
| SCHEMBL31152022 | 0.72 | SMPD1 (0.41) | SMPD1PDE4DMEN1CYP1A2POLB | |
| SCHEMBL3166964 | 0.70 | SMPD1 (0.39) | SMPD1CYP3A4 | |
| SCHEMBL2211604 | 0.69 | CA1 (0.33) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL28238937 | 0.69 | CA1 (0.45) | SMPD1MEN1KMT2A | |
| SCHEMBL5262973 | 0.65 | PDE4D (0.40) | SMPD1PDE4DFOSTTRJUN | |
| SCHEMBL14283817 | 0.62 | GCGR (0.42) | SMPD1KMT2A | |
| SCHEMBL9714494 | 0.61 | DHODH (0.42) | CYP3A4TSHRKMT2AALOX15ALOX12 | |
| SCHEMBL69925 | 0.61 | TDP1 (0.52) | PDE4DMEN1CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |