Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | PRKCI | P41743 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489937 | 0.81 | P2RX7 (0.55) | P2RX7ALDH1A1PRKCIKDM4EGAA | |
| SCHEMBL26693008 | 0.73 | P2RX7 (0.66) | P2RX7ALDH1A1PRKCIKDM4ECTSD | |
| SCHEMBL112991 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGAANPC1 | |
| SCHEMBL107347 | 0.70 | P2RX7 (0.66) | P2RX7ALDH1A1PRKCIKDM4EHPGD | |
| SCHEMBL27212635 | 0.70 | GRM4 (0.55) | P2RX7ALDH1A1KDM4EHDAC3HDAC4 | |
| SCHEMBL4915812 | 0.70 | P2RX7 (0.66) | P2RX7ALDH1A1PRKCIKDM4EGAA | |
| SCHEMBL27947323 | 0.70 | MET (0.43) | ALDH1A1KDM4EHPGDARNPC1 | |
| SCHEMBL7535578 | 0.69 | PARP1 (0.45) | P2RX7ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11816828 | 0.69 | CASP3 (0.52) | ALDH1A1HPGDARNPC1RAB9A | |
| SCHEMBL8696098 | 0.69 | P2RX7 (0.51) | P2RX7ALDH1A1PRKCIKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987255-B1 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |