Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149469 | 0.90 | P2RY6 (0.42) | HSD17B10P2RY6TDP1KDM4ELMNA | |
| SCHEMBL7209073 | 0.82 | HSD17B10 (0.36) | HSD17B10P2RY6KDM4EOPRD1CA1 | |
| SCHEMBL2597556 | 0.81 | TDP1 (0.44) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL668012 | 0.80 | TDP1 (0.41) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL7205496 | 0.80 | P2RY6 (0.53) | HSD17B10P2RY6TDP1KDM4ELMNA | |
| SCHEMBL7202500 | 0.80 | HSD17B10 (0.46) | HSD17B10P2RY6TDP1KDM4ELMNA | |
| SCHEMBL1462666 | 0.78 | HSD17B10 (0.42) | HSD17B10P2RY6OPRD1CA1CA2 | |
| SCHEMBL7367941 | 0.76 | KCNH2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL6574053 | 0.76 | OPRD1 (0.33) | HSD17B10P2RY6OPRD1 | |
| SCHEMBL9278053 | 0.75 | P2RY6 (0.52) | HSD17B10P2RY6TDP1TSHROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824986-A | Metal chelate protein conjugate | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1989-04-25 | — | — | US | claimed |
| EP-0220279-A1 | METHOD OF FORMING A METAL CHELATE PROTEIN CONJUGATE | GANSOW, Otto A. (US) | 1987-05-06 | — | — | EP | claimed |
| WO-1986006384-A1 | METHOD OF FORMING A METAL CHELATE PROTEIN CONJUGATE | GANSOW OTTO A (US) | 1986-11-06 | — | — | WO | claimed |
| EP-3736264-A1 | A NON-RADIOACTIVE IMMUNO-ASSAY FOR 3,5-DIIODO-O-[3-IODOPHENYL]-L-TYROSINE DETECTION AND QUANTITATION | Bracco Imaging SPA (IT) | 2020-11-11 | — | — | EP | disclosed |
| EP-3260443-B1 | A PHARMACEUTICAL COMPOSITION COMPRISING A SULFATED DERIVATIVE OF 3,5-DIIODO-O-[3-IODOPHENYL]-L-TYROSINE | BRACCO IMAGING SPA (IT) | 2020-10-07 | — | — | EP | disclosed |
| US-10457635-B2 | Process for the preparation of a sulfated derivative of 3,5-diiodo-o-[3-iodophenyl]-l-tyrosine | BRACCO IMAGING S.P.A. (IT) | 2019-10-29 | — | — | US | disclosed |
| US-10238615-B2 | 3,5,3′-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof | BRACCO S.P.A. (IT) | 2019-03-26 | — | — | US | disclosed |
| US-10137208-B2 | Vivo tumor targeting and spectroscopic detection with surface-enhanced raman nanoparticle tags | EMORY UNIVERSITY (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180118669-A1 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine | BRACCO IMAGING S.P.A. (IT) | 2018-05-03 | — | — | US | disclosed |
| US-9890116-B2 | Process for the preparation of a sulfated derivative of 3,5-diiodo-O-[3-iodophenyl]-L-tyrosine | BRACCO IMAGING S.P.A. (IT) | 2018-02-13 | — | — | US | disclosed |
| EP-3260443-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING A SULFATED DERIVATIVE OF 3,5-DIIODO-O-[3-IODOPHENYL]-L-TYROSINE | Bracco Imaging SPA (IT) | 2017-12-27 | — | — | EP | disclosed |
| US-5338532-A | Star polymer as carrier for drugs, agricultural compounds | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5271924-A | Low molecular weight polysaccharide complexes for nuclear magnetic resonance imaging | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0420942-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0353450-A1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | THE DOW CHEMICAL COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989012631-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-28 | — | — | WO | disclosed |
| US-4824986-A | Metal chelate protein conjugate | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0271180-A1 | Starburst conjugates | THE DOW CHEMICAL COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988001179-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001178-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457635-B2 | Process for the preparation of a sulfated derivative of 3,5-diiodo-o-[3-iodophenyl]-l-tyrosine | TH, TYRO3, TYR | HSD17B10 2512/4885P2RY6 875/4885TDP1 3140/4885 |
| US-20180118669-A1 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine | TH, TYRO3, TYR | HSD17B10 2512/4885P2RY6 875/4885TDP1 3140/4885 |
| US-10238615-B2 | 3,5,3′-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof | TPO, THRA, THRB | HSD17B10 546/4885P2RY6 3310/4885TDP1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.