Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212676 | 0.80 | RAF1 (0.33) | RAF1BRAF | |
| SCHEMBL28612623 | 0.71 | DPYD (0.35) | — | |
| SCHEMBL8199196 | 0.70 | LMNA (0.52) | — | |
| SCHEMBL7205716 | 0.70 | LMNA (0.52) | — | |
| SCHEMBL5694120 | 0.68 | MEN1 (0.39) | — | |
| SCHEMBL7064418 | 0.67 | MEN1 (0.41) | — | |
| SCHEMBL7063733 | 0.65 | ALDH1A1 (0.43) | — | |
| SCHEMBL7205823 | 0.64 | — | — | |
| SCHEMBL7204392 | 0.61 | MEN1 (0.31) | — | |
| SCHEMBL7064550 | 0.61 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |