Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212661 | 0.84 | CSNK2A2 (0.37) | KMT2A | |
| SCHEMBL7204392 | 0.81 | MEN1 (0.31) | KMT2A | |
| SCHEMBL7205824 | 0.80 | RAF1 (0.34) | RAF1BRAF | |
| SCHEMBL3825844 | 0.77 | LMNA (0.41) | — | |
| SCHEMBL7206799 | 0.77 | LMNA (0.33) | KMT2A | |
| SCHEMBL7205752 | 0.76 | BCHE (0.41) | — | |
| SCHEMBL7204740 | 0.76 | TSHR (0.38) | KMT2A | |
| SCHEMBL7211139 | 0.76 | SMN1; SMN2 (0.34) | KMT2A | |
| SCHEMBL7207482 | 0.75 | LMNA (0.35) | KMT2A | |
| SCHEMBL7208761 | 0.74 | BCHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |