Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207749 | 0.83 | GRM5 (0.35) | GRM5POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7201310 | 0.77 | VCP (0.57) | GRM5RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7203118 | 0.76 | KCNK3 (0.45) | GRM5RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7204957 | 0.73 | VCP (0.53) | GRM5RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7202005 | 0.72 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL7204989 | 0.72 | CES2 (0.45) | POLBRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7202023 | 0.71 | ALDH1A1 (0.51) | POLBRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7845479 | 0.71 | VCP (0.50) | GRM5RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL7205459 | 0.70 | GRM5 (0.38) | GRM5KMT2AALDH1A1MAPTERN1 | |
| SCHEMBL7199134 | 0.70 | CTNNB1 (0.50) | RAB9ANPC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | GRM5 1963/4885POLB 4420/4885RAB9A 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.