SCHEMBL7206079

SCHEMBL7206079

C=CC(SC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 4/20 0.34
CYP3A4 P08684 3/20 0.34
ALOX15 P16050 3/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.33
TSHR P16473 2/20 0.33
USP2 O75604 2/20 0.33
TP53 P04637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
DPP4 P27487 2/20 0.33
ALOX12 P18054 1/20 0.33
F2 P00734 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776368 0.81 CYP2C19 (0.36) LMNACYP2C19KDM4EMAPTCYP3A4
SCHEMBL776296 0.81 CYP2C19 (0.36) LMNACYP2C19KDM4EMAPTCYP3A4
SCHEMBL10404002 0.77 TSHR (0.33) LMNACYP2C19CYP3A4TSHRTDP1
SCHEMBL28201035 0.77 CYP2D6 (0.39) LMNAALDH1A1TSHRDPP4F2
SCHEMBL776369 0.77 CYP2C19 (0.34) LMNACYP2C19KDM4EMAPTCYP3A4
SCHEMBL19614987 0.77 CFTR (0.44) LMNAKDM4EMAPTTSHRHSD17B10
SCHEMBL9112613 0.76 KDM4E (0.33) LMNACYP2C19KDM4EMAPTCYP3A4
SCHEMBL21870359 0.76 MEN1 (0.35) LMNAKDM4EALDH1A1TSHRTDP1
SCHEMBL9068192 0.75 ALDH1A1 (0.42) LMNACYP2C19KDM4EMAPTCYP3A4
SCHEMBL2146150 0.74 LMNA (0.35) LMNACYP2C19ALDH1A1TDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1161092-A None JP disclosed
US-6610458-B2 Applying coating to printing cylinder which changes affinity for printing fluid upon exposure to radiation; lithography KODAK POLYCHROME GRAPHICS LLC 2003-08-26 US disclosed
US-6423469-B1 IONOMER COMPRISING UNSATURATED COMONOMERS OF QUATERNIZED N-ALKYLATED AROMATIC HETEROCYCLIC, ORGANOONIUM, AND THIOSULFATE COMPOUNDS; LITHOGRAPHY EASTMAN KODAK COMPANY 2002-07-23 US disclosed
US-6410202-B1 HYDROPHILIC HEAT SENSITIVE ELEMENTS EASTMAN KODAK COMPANY 2002-06-25 US disclosed
US-6399268-B1 Processless direct write imaging member containing polymer grafted carbon and methods of imaging and printing KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
US-5264125-A Cationic or anionic addition monomer with crosslinking monomer and a diluent for nonporous membranes IONICS' INCORPORATED (US) 1993-11-23 US disclosed
US-5145618-A Passing sandwich of support substrate and pliable foil with polymerizable liquid between rolls, separating solid polymer sheet IONICS, INCORPORATED (US) 1992-09-08 US disclosed
JP-H01161092-A PERFUME LION CORP 1989-06-23 JP disclosed