SCHEMBL9068192

SCHEMBL9068192

C=CC(SC(C)O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HBB P68871 1/20 0.40
LMNA P02545 3/20 0.39
ADRA2C P18825 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ADRA2A P08913 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
CHRM2 P08172 1/20 0.37
ADRA1A P35348 1/20 0.37
RGS12 O14924 1/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776296 0.83 CYP2C19 (0.36) ALDH1A1LMNAKDM4ECYP2C19CYP3A4
SCHEMBL7206079 0.75 LMNA (0.35) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL776368 0.74 CYP2C19 (0.36) ALDH1A1LMNAKDM4ECYP2C19CYP3A4
SCHEMBL9153275 0.73 RIPK1 (0.33) LMNAKDM4ECYP2C9CYP2C19CYP3A4
SCHEMBL20854763 0.73 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AHBBLMNA
SCHEMBL9067800 0.72 CYP2C19 (0.37) ALDH1A1LMNAKDM4ECYP2C9CYP2C19
SCHEMBL23221180 0.71 KDM4E (0.56) ALDH1A1MEN1KMT2AHBBLMNA
SCHEMBL8287058 0.71 KDM4E (0.56) ALDH1A1MEN1KMT2AHBBLMNA
Bromide SCHEMBL20854776 0.71 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AHBBLMNA
SCHEMBL9201789 0.71 KDM4E (0.56) ALDH1A1MEN1KMT2AHBBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543482-A Composition for high refractive index lens comprising copolymer of vinylbenzylthio compound and a monomer copolymerizable therewith MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1996-08-06 US disclosed