SCHEMBL28201035

SCHEMBL28201035

CSC(C=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.39
KMT2A Q03164 2/20 0.38
SRC P12931 1/20 0.34
ALOX5 P09917 1/20 0.34
LMNA P02545 2/20 0.33
DPP4 P27487 2/20 0.33
MAPK1 P28482 1/20 0.33
F2 P00734 1/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2A6 P11509 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10951502 0.78 CYP3A4 (0.39) KMT2AL3MBTL1MEN1
SCHEMBL3119634 0.78 ADRB2 (0.40) LMNAMAPK1TSHRCYP2A6
SCHEMBL10404002 0.77 TSHR (0.33) CYP2D6LMNADPP4F2TSHR
SCHEMBL7206079 0.77 LMNA (0.35) KMT2ALMNADPP4F2TSHR
SCHEMBL15564590 0.77 CFTR (0.44) LMNATSHRCYP2A6L3MBTL1
SCHEMBL21870359 0.76 MEN1 (0.35) CYP2D6KMT2ALMNADPP4F2
SCHEMBL23628841 0.72 TSHR (0.38) CYP2D6KMT2ASRCLMNADPP4
SCHEMBL31347982 0.72 CYP2D6 (0.35) CYP2D6KMT2AALOX5LMNAALDH1A1
SCHEMBL4068170 0.72 TSHR (0.38) CYP2D6KMT2ASRCLMNADPP4
SCHEMBL8812923 0.72 TRPA1 (0.35) CYP2D6KMT2ASRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107556223-A A kind of preparation method of 4 mesyl phenylacetic acid 孙家强 2018-01-09 CN disclosed