Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 17/20 | 0.71 |
| ▸ | NPC1 | O15118 | 15/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 11/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059841 | 0.84 | ALDH1A1 (0.73) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13762461 | 0.84 | KDM4E (0.70) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13930785 | 0.83 | ALDH1A1 (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13930781 | 0.83 | ALDH1A1 (0.71) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3263307 | 0.83 | KDM4E (0.71) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16771498 | 0.83 | ATAD2 (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29454512 | 0.83 | ATAD2 (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13930783 | 0.81 | KDM4E (0.68) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22471879 | 0.80 | ATAD2 (0.61) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL601473 | 0.80 | NPC1 (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618145-B2 | Small molecular compounds capable of accelerating proliferation of stem cells and use thereof | HAN MEI (CN) | 2013-12-31 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | MKI67, KIT, PCNA | RAB9A 2617/4885NPC1 2926/4885KDM4E 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.