Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.71 |
| ▸ | RAB9A | P51151 | 14/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.71 |
| ▸ | NPC1 | O15118 | 12/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 9/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059841 | 0.84 | ALDH1A1 (0.73) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13762461 | 0.84 | KDM4E (0.70) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13930785 | 0.83 | ALDH1A1 (1.00) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL720619 | 0.83 | RAB9A (0.71) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13930781 | 0.83 | ALDH1A1 (0.71) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13930786 | 0.83 | ATAD2 (0.69) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13930783 | 0.81 | KDM4E (0.68) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL21887193 | 0.80 | NPC1 (0.79) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1453166 | 0.80 | KDM4E (1.00) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL12171933 | 0.78 | RAB9A (0.67) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | claimed |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-07-11 | — | — | US | claimed |
| US-10112930-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2018-10-30 | — | — | US | claimed |
| EP-2786993-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-11-15 | — | — | EP | claimed |
| WO-2017106715-A1 | COMPOSITION AND METHODS FOR REDUCING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-22 | — | — | WO | claimed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | claimed |
| EP-2786993-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | claimed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | claimed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885RAB9A 3412/4885ALDH1A1 3430/4885 |
| US-10112930-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885RAB9A 3412/4885ALDH1A1 3430/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885RAB9A 3412/4885ALDH1A1 3430/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885RAB9A 3412/4885ALDH1A1 3430/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | KDM4E 2135/4885RAB9A 4578/4885ALDH1A1 2842/4885 |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | RPL41, SPOUT1, MASTL | KDM4E 1862/4885RAB9A 4191/4885ALDH1A1 4221/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885RAB9A 3412/4885ALDH1A1 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.