SCHEMBL7206853

SCHEMBL7206853

COc1cccc(C(c2ccccc2)(c2ccccc2OC)[C@@]2(n3ccc(=O)[nH]c3=O)O[C@H](CO)C[C@H]2O)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DUT P33316 10/20 0.32
HRH4 Q9H3N8 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7209223 0.86 SLC28A1 (0.32) DUT
SCHEMBL7206858 0.84 DUT (0.33) DUT
SCHEMBL6318834 0.82 DUT (0.33) DUT
SCHEMBL7212072 0.81 DUT (0.31) DUT
SCHEMBL5671911 0.78 SLC28A1 (0.35) DUT
SCHEMBL7209224 0.75 SLC28A1 (0.33) DUT
SCHEMBL14764632 0.73
SCHEMBL10336767 0.73 DUT (0.32) DUT
SCHEMBL7212076 0.73 DUT (0.32) DUT
SCHEMBL1739169 0.69 PDE3A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785278-B1 METHOD FOR DETERMINING DNA NUCLEOTIDE SEQUENCE RIKAGAKU KENKYUSHO (JP) 2003-02-05 EP disclosed
US-6074824-A Method for determining DNA nucleotide sequence THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2000-06-13 US disclosed
EP-0785278-A1 METHOD OF DNA SEQUENCING THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 1997-07-23 EP disclosed