⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318834 | 0.89 | DUT (0.33) | — | |
| SCHEMBL7209223 | 0.76 | SLC28A1 (0.32) | — | |
| SCHEMBL7863893 | 0.74 | RNASE1 (0.37) | — | |
| SCHEMBL7206853 | 0.73 | DUT (0.32) | — | |
| SCHEMBL5671911 | 0.72 | SLC28A1 (0.35) | — | |
| SCHEMBL9755145 | 0.71 | RNASE1 (0.38) | — | |
| SCHEMBL7212072 | 0.71 | DUT (0.31) | — | |
| SCHEMBL1706305 | 0.70 | RNASE1 (0.38) | — | |
| SCHEMBL7209224 | 0.69 | SLC28A1 (0.33) | — | |
| SCHEMBL20636773 | 0.69 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753607-B1 | BICYCLO[6.1.0]NON-4-YNE REAGENTS FOR CHEMICAL MODIFICATION OF OLIGONUCLEOTIDES | BERRY AND ASSOCIATES INC (US) | 2016-04-13 | — | — | EP | disclosed |
| US-20130066063-A1 | BICYCLO[6.1.0]NON-4-YNE REGENTS FOR CHEMICAL MODIFICATION OF OLIGONUCLEOTIDES | BERRY AND ASSOCIATES, INC. | 2013-03-14 | — | — | US | disclosed |