SCHEMBL7206858

SCHEMBL7206858

COO[C@@H]1C[C@@H](CO)O[C@]1(n1ccc(=O)[nH]c1=O)C(c1ccccc1)(c1ccccc1)c1cccc(OC)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DUT P33316 16/20 0.33
OPRM1 P35372 1/20 0.31
KCNH2 Q12809 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TP53 P04637 1/20 0.31
GRM2 Q14416 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7206853 0.84 DUT (0.32) DUT
SCHEMBL7209224 0.82 SLC28A1 (0.33) DUTTP53TYMP
SCHEMBL5671911 0.81 SLC28A1 (0.35) DUTTP53TYMP
SCHEMBL7212076 0.77 DUT (0.32) DUTTP53TYMP
SCHEMBL7209223 0.76 SLC28A1 (0.32) DUT
SCHEMBL7212072 0.74 DUT (0.31) DUT
SCHEMBL6318834 0.74 DUT (0.33) DUT
SCHEMBL29834207 0.71 SLC28A1 (0.35) DUTTYMP
SCHEMBL4085513 0.68 SLC28A1 (0.43) DUT
SCHEMBL14764632 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785278-B1 METHOD FOR DETERMINING DNA NUCLEOTIDE SEQUENCE RIKAGAKU KENKYUSHO (JP) 2003-02-05 EP disclosed
US-6074824-A Method for determining DNA nucleotide sequence THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2000-06-13 US disclosed
EP-0785278-A1 METHOD OF DNA SEQUENCING THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 1997-07-23 EP disclosed