Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.47 |
| ▸ | HTR1E | P28566 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211948 | 0.99 | CHRM3 (0.48) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL7206890 | 0.79 | CHRM3 (0.44) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL7211946 | 0.78 | CHRM3 (0.45) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL7211288 | 0.77 | PTGS2 (0.41) | LMNAMAPTCYP3A4ADRA2AKCNH2 | |
| SCHEMBL7207551 | 0.77 | L3MBTL1 (0.56) | LMNAMAPTCYP3A4 | |
| SCHEMBL7211248 | 0.72 | LMNA (0.57) | LMNAMAPTHTT | |
| SCHEMBL10298827 | 0.72 | LMNA (0.58) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL7103544 | 0.72 | SLC6A2 (0.62) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL28373611 | 0.71 | HTR1E (0.65) | CHRM3HTR1ES1PR3LMNAMEN1 | |
| SCHEMBL69127 | 0.71 | HTR1E (0.65) | CHRM3HTR1ES1PR3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |
| EP-0698010-A1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-02-28 | — | — | EP | claimed |