Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207210 | 0.82 | KDM4E (0.34) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL14027306 | 0.77 | SPHK2 (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL4361737 | 0.77 | SPHK2 (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL4820163 | 0.77 | KDM4E (0.47) | KDM4ECCR5MEN1KMT2ATDP1 | |
| SCHEMBL14027308 | 0.77 | SPHK2 (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL4366788 | 0.77 | SPHK2 (0.42) | KDM4EALDH1A1CCR5MEN1KMT2A | |
| SCHEMBL4159635 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHR | |
| Formic Acid SCHEMBL4908786 | 0.75 | SPHK2 (0.42) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL7205738 | 0.74 | FAAH (0.39) | KDM4ECCR5MEN1KMT2AFAAH | |
| SCHEMBL14027327 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1CCR5MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | claimed |