Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799632 | 0.89 | LSS (0.43) | LSSKMT2A | |
| SCHEMBL4799635 | 0.89 | LSS (0.43) | LSSKMT2A | |
| SCHEMBL7211880 | 0.80 | SMN1; SMN2 (0.44) | LSSALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7211877 | 0.80 | SMN1; SMN2 (0.44) | LSSALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7211442 | 0.79 | LMNA (0.39) | LSSALDH1A1POLBKMT2AMAPT | |
| SCHEMBL7211436 | 0.79 | LMNA (0.39) | LSSALDH1A1POLBKMT2AMAPT | |
| SCHEMBL7209307 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMAPTHPGDHTT | |
| SCHEMBL7208602 | 0.77 | LMNA (0.41) | LSSKMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL7208600 | 0.77 | LMNA (0.41) | LSSKMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL7209436 | 0.77 | FPR3 (0.42) | LSSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |