Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212742 | 0.90 | HPRT1 (0.39) | CTSLKMT2AHPRT1LAP3ANPEP | |
| SCHEMBL7207832 | 0.83 | MEN1 (0.41) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL7361409 | 0.79 | ATM (0.46) | PIN1CTSLATMALDH1A1LMNA | |
| SCHEMBL9715661 | 0.77 | POLB (0.48) | PIN1CTSLATMHPRT1ALDH1A1 | |
| SCHEMBL7209082 | 0.76 | NPC1 (0.46) | CTSLMMETACR1LAP3ANPEP | |
| SCHEMBL28460302 | 0.76 | TACR1 (0.43) | CTSLMMETACR1ALDH1A1 | |
| SCHEMBL7207869 | 0.76 | NPC1 (0.46) | CTSLMMETACR1LAP3ANPEP | |
| SCHEMBL7207845 | 0.73 | MEN1 (0.40) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL7105161 | 0.73 | MEN1 (0.40) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL4958184 | 0.71 | ALPI (0.58) | PIN1LAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |