Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.41 |
| ▸ | RARA | P10276 | 7/20 | 0.41 |
| ▸ | RARG | P13631 | 7/20 | 0.41 |
| ▸ | RXRA | P19793 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207886 | 1.00 | RARB (0.41) | RARBRARARARGRXRAMEN1 | |
| SCHEMBL7207116 | 0.87 | RARB (0.44) | RARBRARARARGRXRAMEN1 | |
| SCHEMBL7207124 | 0.87 | RARB (0.44) | RARBRARARARGRXRAMEN1 | |
| SCHEMBL8904571 | 0.86 | CYSLTR2 (0.35) | RARBRARARARGRXRA | |
| SCHEMBL7208504 | 0.78 | RXRA (0.48) | RARBRARARARGRXRAMEN1 | |
| SCHEMBL7208507 | 0.78 | RXRA (0.48) | RARBRARARARGRXRAMEN1 | |
| SCHEMBL14017871 | 0.77 | RARB (0.50) | RARBRARARARGRXRAALDH1A1 | |
| SCHEMBL7212228 | 0.77 | RARB (0.63) | RARBRARARARGRXRAALDH1A1 | |
| SCHEMBL4669367 | 0.77 | RARB (0.63) | RARBRARARARGRXRAALDH1A1 | |
| SCHEMBL10842696 | 0.77 | RARB (0.63) | RARBRARARARGRXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | claimed |
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |