Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 2/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207886 | 0.86 | RARB (0.41) | RXRARARBRARARARG | |
| SCHEMBL7207891 | 0.86 | RARB (0.41) | RXRARARBRARARARG | |
| SCHEMBL8905607 | 0.78 | RXRA (0.42) | CYSLTR2CYSLTR1PLK1PPARAPPARG | |
| SCHEMBL8906010 | 0.76 | RXRA (0.49) | CYSLTR2CYSLTR1PLK1RXRATRPA1 | |
| SCHEMBL8906153 | 0.74 | RXRA (0.45) | RXRA | |
| SCHEMBL8905251 | 0.72 | RXRA (0.53) | RXRARARBRARARARG | |
| SCHEMBL8910622 | 0.72 | RXRA (0.43) | RXRARARBRARARARG | |
| SCHEMBL7207124 | 0.71 | RARB (0.44) | RXRARARBRARARARG | |
| SCHEMBL7207116 | 0.71 | RARB (0.44) | RXRARARBRARARARG | |
| SCHEMBL8905583 | 0.69 | THRA (0.34) | CYSLTR2CYSLTR1PPARAPPARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |