Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 6/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553506 | 0.86 | LAP3 (0.47) | LAP3ANPEPSRRACP3ALDH1A1 | |
| SCHEMBL7208497 | 0.86 | LAP3 (0.37) | LAP3ANPEPSRRACP3ALDH1A1 | |
| SCHEMBL7208511 | 0.84 | LAP3 (0.39) | LAP3ANPEPCTRB1TSHRSRR | |
| SCHEMBL6555636 | 0.84 | ALDH1A1 (0.38) | LAP3TSHRALDH1A1 | |
| SCHEMBL20856237 | 0.75 | HSD17B10 (0.40) | — | |
| SCHEMBL7114956 | 0.74 | LAP3 (0.44) | LAP3ANPEPCTRB1PPARGPPARA | |
| SCHEMBL29371149 | 0.73 | ALDH1A1 (0.40) | TSHRALDH1A1 | |
| SCHEMBL4748270 | 0.73 | ALPI (0.56) | LAP3ANPEPSRRACP3SLC15A1 | |
| SCHEMBL29761129 | 0.73 | ALPI (0.56) | LAP3ANPEPSRRACP3SLC15A1 | |
| Phosphoramidic Acid SCHEMBL1691253 | 0.72 | ALPI (0.54) | LAP3ANPEPSRRACP3SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |